Active Pharmaceutical Ingredients
ACECLOFENAC | ACEBROPHYLLINE | AMISULPRIDE | ATORVASTATIN | BACLOFEN | BROMHEXINE HCL | CINNARIZINE | CLOBETASOL | CLOMIPHENE CITRATE | CLOPIDOGREL BISULPHATE | DIPHENHYDRAMINE BASE/ HCL | DISULPHIRAM

 

ACECLOFENAC

ACECLOFENAC cas no 89796-99-6
ACECLOFENAC Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) analog of Diclofenac. It is used for the relief of pain and inflammation in rheumatoid arthritis, osteoarthritis and ankylosing spondylitis. Aceclofenac has higher anti-inflammatory action than conventional NSAIDs. It is a cytokine inhibitor. Aceclofenac works by blocking the action of a substance in the body called cyclo-oxygenase. Cyclo-oxygenase is involved in the production of prostaglandins (chemicals in the body) which cause pain, swelling and inflammation. Aceclofenac is the glycolic acid ester of diclofenac.

ACEBROPHYLLINE

ACEBROPHYLLINE cas no 134523-00-5
ACEBROPHYLLINE Acebrophylline, a xanthine derivative, is prescribed as a bronchodilator for the treatment of bronchial asthma and COPD in adults. Acebrophylline alter mucus gel secretion phase by lowering viscosity and increasing the serous gel phase. By augmenting ciliary motility, Acebrophylline increases the mucociliary clearance.

AMISULPRIDE

AMISULPRIDE cas no 71675-85-9
Amisulpride is an atypical antipsychotic used to treat psychosisin schizophrenia and episodes of mania in bipolar disorder. In Italy, it is also used as a treatment for dysthymia.

ATORVASTATIN

ATORVASTATIN cas no 96989-76-3
Atorvastatin is in a group of drugs called HMG CoA reductase inhibitors, or “statins.” Atorvastatin reduces levels of “bad” cholesterol (low-density lipoprotein, or LDL) and triglycerides in the blood, while increasing levels of “good” cholesterol (high-density lipoprotein, or HDL).Atorvastatin is used to treat high cholesterol, and to lower the risk of stroke, heart attack, or other heart complications in people with type 2 diabetes, coronary heart disease, or other risk factors.Atorvastatin is used in adults and children who are at least 10 years old.

BACLOFEN

BACLOFEN cas no 1134-47-0
Baclofen is a centrally-acting skeletal muscle relaxant. It is a derivative of gamma-aminobutyric acid (GABA). It is primarily used to treat spasticity and is in the early research stages for use for the treatment of alcoholism. It is also used by compounding pharmacies in topical pain creams as a muscle relaxant.It is a GABA receptor agonist, specifically for the GABAB receptors.[1][2] Its beneficial effects in spasticity result from actions at spinal and supraspinal sites. Baclofen can also be used to treat hiccups.

BROMHEXINE HCL

BROMHEXINE HCL cas no 3572-43-8
Bromhexine is a mucolytic (expectorant) agent used in the treatment of respiratory disorders associated with viscid or excessive mucus. In addition, bromhexine has antioxidant properties.Bromhexine is intended to support the body’s mechanisms for clearing mucus from the respiratory tract.Bromhexine is a synthetic derivative of the herbal active ingredient vasicine. It has been shown to increase the proportion of serous bronchial secretion, making it more easily expectorated.

CINNARIZINE

CINNARIZINE cas no 298-57-7
Cinnarizine is a drug derivative of piperazine, and characterized as an antihistamine and a calcium channel blocker, it is also known to promote cerebral blood flow, and so is used to treat cerebral apoplexy, post-trauma cerebral symptoms, and cerebral arteriosclerosis.However, it is more commonly prescribed for nausea and vomiting due to motion sickness or other sources such as chemotherapy,vertigoor Ménière’s disease.

CLOBETASOL

CLOBETASOL cas no 25122-46-7
Reducing itching, redness, and swelling associated with many skin conditions.Clobetasol cream is a topical corticosteroid. It works by decreasing certain immune responses, which reduces redness and itching of skin.

CLOMIPHENE CITRATE

CLOMIPHENE CITRATE cas no 911-45-5
Clomiphene is a non-steroidal fertility medicine. It causes the pituitary gland to release hormones needed to stimulate ovulation (the release of an egg from the ovary).Clomiphene is used to cause ovulation in women with certain medical conditions (such as polycystic ovary syndrome) that prevent naturally occurring ovulation.

CLOPIDOGREL BISULPHATE

CLOPIDOGREL BISULPHATE cas no 113665-84-2
Clopidogrel (INN) is an oral, thienopyridine-class antiplatelet agent used to inhibit blood clots in coronary artery disease, peripheral vascular disease, cerebrovascular disease, and to prevent myocardial infarction (heart attack). It is marketed by Bristol-Myers Squibb and Sanofi under the trade name Plavix. The drug works by irreversibly inhibiting a receptor called P2Y12, an adenosine diphosphate (ADP) chemoreceptor on platelet cell membranes. Adverse effects include bleeding, severeneutropenia, and thrombotic thrombocytopenic purpura

DIPHENHYDRAMINE BASE/ HCL

DIPHENHYDRAMINE BASE/ HCL cas no 58-73-1
Diphenhydramine is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.Diphenhydramine is used to treat sneezing, runny nose, watery eyes, hives, skin rash, itching, and other cold or allergy symptoms.Diphenhydramine is also used to treat motion sickness, to induce sleep, and to treat certain symptoms of Parkinson’s disease.

DISULPHIRAM

DISULPHIRAM cas no 97-77-8
Disulfiram is used forTreating alcoholism.Disulfiram is an alcohol-abuse deterrent. It works by blocking the breakdown of alcohol, causing unpleasant side effects (eg, vomiting, upset stomach) when even a small amount of alcohol is consumed.Disulfiram is also being studied as a treatment for cocaine dependence, as it prevents the breakdown of dopamine (a neurotransmitter whose release is stimulated by cocaine); the excess dopamine results in increased anxiety, higher blood pressure, restlessness, and other unpleasant symptoms

DIMINAZEN

DIMINAZEN cas no 536-71-0
Diminazen(e) is an antiinfective drug for animals e.g., against infections with Babesia,Trypanosoma and Cytauxzoon and some bacteria such as Brucella and Streptococcus.Chemically it is a di-amidine, and it is used in form of the aceturate (N-acetylglycinate).

DOMPERIDONE

DOMPERIDONE cas no 57808-66-9
Domperidone is given in order to relieve nausea and vomiting; to increase the transit of food through the stomach (as a prokinetic agent through increase in gastrointestinal peristalsis); and to increase lactation (breast milk production) by release of prolactin. It is also used in the scientific study of the way dopamine (an important neurotransmitter) acts in the body.

DOXOFYLLINE

DOXOFYLLINE cas no 69975-86-6
Doxofylline , (also known as doxophylline) is a xanthine derivative drug used in the treatment of asthma.It has antitussive and bronchodilator[2] effects, and acts as a phosphodiesterase inhibitor

DROTAVERINE

DROTAVERINE cas no 985-12-6
Drotaverine (INN, also known as drotaverin) is an antispasmodic drug, used to enhance cervical dilation during childbirth.It is structurally related to papaverine, is a selective inhibitor of phosphodiesterase 4, and has no anticholinergic effects.

EPERISONE

EPERISONE cas no 56839-43-1
Eperisone (formulated as the eperisone hydrochloride salt) is an antispasmodic drug.Eperisone acts by relaxing both skeletal muscles and vascular smooth muscles, and demonstrates a variety of effects such as reduction of myotonia, improvement ofcirculation, and suppression of the pain reflex. The drug inhibits the vicious circle of myotonia by decreasing pain, ischaemia, and hypertonia in skeletal muscles, thus alleviating stiffness and spasticity, and facilitating muscle movement.Eperisone also improves dizziness and tinnitus associated with cerebrovascular disorders or cervical spondylosis.Eperisone has a relatively low incidence of sedation when compared with other antispasmodic drugs; this simplifies the clinical application of the drug and makes it an attractive choice for patients who require antispasmodic therapy without a reduction in alertness.

ETAMSYLATE

ETAMSYLATE cas no 2624-44-4
Ethamsylate is a haemostatic drug.It is believed to work by increasing capillary endothelial resistance and promoting platelet adhesion.It also inhibits biosynthesis and action of those prostaglandins which cause platelet disaggregation, vasodilation and increased capillary permeability.

ETODOLAC

ETODOLAC cas no 41340-25-4
Etodolac is a nonsteroidal anti-inflammatory drug (NSAIDs). It works by reducing hormones that cause inflammation and pain in the body. NSAIDs treat the symptoms of pain and inflammation. They do not treat the disease that causes those symptoms.Etodolac is used to treat pain or inflammation caused by arthritis or osteoarthritis.Etodolac may also be used for purposes other than those listed in this medication guide.

FEBUXOSTAT

FEBUXOSTAT cas no 144060-53-7
Febuxostat is a drug that inhibits xanthine oxidase, thus reducing production of uric acid in the body. It is used in the treatment of chronic gout and hyperuricemia.

FENOFIBRATE

FENOFIBRATE cas no 49562-28-9
Fenofibrate helps reduce cholesterol and triglycerides (fatty acids) in the blood. High levels of these types of fat in the blood are associated with an increased risk of atherosclerosis (clogged arteries).Fenofibrate is used to treat high cholesterol and high triglyceride levels.

FLAVOXATE

FLAVOXATE cas no 15301-69-6
Relieving pain, frequency, and urgency of urination as well as nighttime urination associated with certain medical conditions. It may be used in combination with other medicines to treat ulcers. It may also be used for other conditions as determined by your doctor.Flavoxate is an anticholinergic. It works by decreasing muscle spasms of the bladder.

FLUCONAZOLE

FLUCONAZOLE cas no 86386-73-4
Treating and preventing certain yeast and fungal infections. It may also be used for other conditions as determined by your doctor.Fluconazole is an azole antifungal. It kills sensitive fungi by interfering with the formation of the fungal cell membrane.

FLUNARIZINE

FLUNARIZINE cas no 52468-60-7
Flunarizine is a drug classified as a calcium channel blocker. Flunarizine is a non-selective calcium entry blocker with other actions including histamine H1 receptor blocking activity.It is effective in the prophylaxis of migraine,[2] occlusive peripheral vascular disease, vertigo of central and peripheral origin, and as an adjuvant in the therapy of epilepsy. It may help to reduce the severity and duration of attacks of paralysis associated with the more serious form of alternating hemiplegia, as well as being effective in rapid onset dystonia-parkinsonism (RDP). Both these conditions share a mutation in the ATP13A gene.

GLUCOSAMINE POTASSIUM SULPHATE

GLUCOSAMINE POTASSIUM SULPHATE cas no 3416-24-8
Glucosamine (C6H13NO5) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids. Glucosamine is part of the structure of the polysaccharides chitosan and chitin, which compose the exoskeletons of crustaceans and other arthropods, as well as the cell walls of fungi and many higher organisms. Glucosamine is one of the most abundant monosaccharides. It is produced commercially by the hydrolysis of crustacean exoskeletons or, less commonly, by fermentation of a grain such as corn or wheat.[2] Glucosamine appears to be safe for use as a dietary supplement; effectiveness has not been established for any condition.

GUAIFENESIN

GUAIFENESIN cas no 93-14-1
Guaifenesin is an expectorant. It helps loosen congestion in your chest and throat, making it easier to cough out through your mouth.Guaifenesin is used to reduce chest congestion caused by the common cold, infections, or allergies.Guaifenesin may also be used for purposes not listed in this medication guide.

ISOMETAMIDIUM

ISOMETAMIDIUM cas no 34301-55-8
Isometamidium chloride is a trypanocidal agent used in veterinary medicine.

LEVOSULPIRIDE

LEVOSULPIRIDE cas no 23672-07-3
Levosulpiride is a substituted benzamide antipsychotic, reported to be a selective antagonist of dopamine D2 receptor activity on both central and peripheral levels. It is an atypical neuroleptic and a prokinetic agent. Levosulpiride is also claimed to have mood elevating properties. Levosulpiride is used in the treatment of psychoses, particularly negative symptoms of schizophrenia, anxiety disorders, dysthymia, vertigo, dyspepsia, irritable bowel syndrome and premature ejaculation.

LEVOCETIRIZINE DIHYDROCHLORIDE

LEVOCETIRIZINE DIHYDROCHLORIDE cas no 130018-77-8
Relief of symptoms associated with seasonal and perennial allergic rhinitis; treatment of uncomplicated skin manifestations of chronic idiopathic urticaria.

LORNOXICAM

LORNOXICAM cas no 70374-39-9
Lornoxicam is a non-steroidal anti-inflammatory drug (NSAID) of the oxicam class with analgesic (pain relieving), anti-inflammatory and antipyretic (fever reducing) properties. It is available in oral and parenteral formulations.

LOSARTAN POTASSIUM

LOSARTAN POTASSIUM cas no 114798-26-4
Treatment of hypertension; nephropathy in type 2 diabetic patients; reduce risk of stroke in patients with hypertension and left ventricular hypertrophy.

LUMEFANTRINE

LUMEFANTRINE cas no 82186-77-4
Lumefantrine (or benflumetol) is an antimalarial drug. It is only used in combination with artemether. The term “co-artemether” is sometimes used to describe this combination.

METHYLSULFONYLMETHANE

METHYLSULFONYLMETHANE cas no 67-71-0
Methylsulfonylmethane (MSM) is an organosulfur compound with the formula (CH3)2SO2. It is also known by several other names including DMSO2, methyl sulfone, and dimethyl sulfone.Methylsulfonylmethane is used forPain and swelling in muscles and joints. It may have other uses as well. Check with your pharmacist for more details regarding the particular brand you use.Methylsulfonylmethane is used as a solvent at some level.

MICONAZOLE NITRATE

MICONAZOLE NITRATE cas no 22916-47-8
Miconazole is commonly applied topically to the skin or to mucous membranes to cure fungal infections.Miconazole is mainly used externally for the treatment of athlete’s foot, ringworm, and jock itch. Internal application is used for oral or vaginal thrush (yeast infection). The oral gel may also be used for the lip disorder angular cheilitis.In the UK, miconazole may be used to treat neonatal oral thrush, while the alternative nystatin is only licensed for patients over the age of one month, but drug interactions are possible.It is on the World Health Organization’s List of Essential Medicines, the most important medications needed in a basic health system.

MISOPROSTOL

MISOPROSTOL cas no 59122-46-2
Reducing the risk of stomach ulcers in certain patients who take nonsteroidal anti-inflammatory drugs (NSAIDs). It may also be used for other conditions as determined by your doctor.Misoprostol is a prostaglandin. It works by reducing the amount of acid released by the stomach and protecting the stomach lining, which helps to reduce the risk of stomach ulcers.

MOXIFLOXACIN

MOXIFLOXACIN cas no 354812-41-2
Treating infections caused by certain bacteria. Moxifloxacin is a fluoroquinolone. It works by killing sensitive bacteria.

NIACINAMIDE

NIACINAMIDE cas no 98-92-0
Treating or preventing low levels of niacin (vitamin B3). It may also be used for other conditions as determined by your doctor.Niacinamide is a vitamin B supplement. It works by replacing vitamin B3 in the body.

NIMESULIDE

NIMESULIDE cas no 51803-78-2
Nimesulide is a relatively COX-2 selective, non-steroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic properties. Its approved indications are thetreatment of acute pain, the symptomatic treatment of osteoarthritis and primary dysmenorrhoea in adolescents and adults above 12 years old. It has a multifactorial mode of action and is characterized by a fast onset of action.

OLMESARTAN MEDOXOMIL

OLMESARTAN MEDOXOMIL cas no 144689-63-4
Olmesartanmedoxomil is an angiotensin II receptor antagonist which has been used for the treatment of high blood pressure.Treatment of hypertension.

PANTOPROZOLE SODIUM SESQUIHYDRATE

PANTOPROZOLE SODIUM SESQUIHYDRATE cas no 102625-70-7
Pantoprazole sodium sesquihydrateis a medicine which is used in a number of conditions – an example is treatment of gastric ulcers.

PHENAZONE

PHENAZONE cas no 60-80-0
Phenazone is an analgesic, a non-steroidal anti-inflammatory drug and an antipyretic.Phenazone, is a pain reliever, and a fever reducer. It is combined in ear drops (otic drops) with benzocaine, a medication used to numb the ear. It is used to relieve ear pain caused by infections, and remove a build up of ear wax.The combination of phenazone (antipyrine) and benzocaine works by reducing pain and discomfort in the ear.

PHENYTOIN SODIUM

PHENYTOIN SODIUM cas no 57-41-0
Phenytoin is used to prevent and control seizures (also called an anticonvulsant or antiepileptic drug). It works by reducing the spread of seizure activity in the brain.Phenytoin is also used to prevent seizures following neurosurgery. Phenytoin is believed to protect against seizures by causing voltage-dependent block of voltage gated sodium channels.[1] Additionally, phenytoin is a class 1b antiarrhythmic that can be used to treat abnormal heart rhythms when conventional options have failed or aftercardiac glycoside poisoning.It is on the World Health Organization’s List of Essential Medicines, a list of the most important medication needed in a basic health system.

PREGABALIN

PREGABALIN cas no 148553-50-8
Treating fibromyalgia or nerve pain caused by certain conditions (eg, shingles, diabetic nerve problems, spinal cord injury). It is also used in combination with other medicines to treat certain types of seizures. It may also be used for other conditions as determined by your doctor.Pregabalin is an anticonvulsant and neuropathic pain agent. Exactly how pregabalin works is not known. It is thought to bind to certain areas in the brain that help reduce seizures, nerve pain, and anxiety.

RACECADOTRIL

RACECADOTRIL cas no 81110-73-8
Racecadotril, is an antidiarrheal drug which acts as a peripherally acting enkephalinase inhibitor.Unlike other opioid medications used to treat diarrhea, which reduce intestinal motility, racecadotril has an antisecretory effect—it reduces the secretion of water and electrolytes into the intestine.

RIFAXIMIN

RIFAXIMIN cas no 80621-81-4
Decreasing the risk that hepatic encephalopathy (a serious liver problem) will occur again in patients who have already had it. It may be used for other conditions as determined by your doctor.Rifaximin is an antibiotic. Exactly how it works to treat hepatic encephalopathy is not known. It is thought to have an effect on the bacteria in the stomach. It has poor oral bioavailability, meaning that very little of the drug will be absorbed into the blood stream when it is taken orally. Rifaximin is used in the treatment of traveler’s diarrhea and hepatic encephalopathy

ROSUVASTATIN CALCIUM

ROSUVASTATIN CALCIUM cas no 287714-41-4
Lowering high cholesterol and triglycerides in certain patients. It also increases high-density lipoprotein (HDL) (“good”) cholesterol levels. It is used to slow atherosclerosis (narrowing of the arteries) in patients with high blood cholesterol levels. It is used in certain patients to reduce the risk of heart attack or stroke.It is also used in certain patients to reduce the need for medical procedures to open blocked heart vessels. It is used along with an appropriate diet. It may also be used for other conditions as determined by your doctor.Rosuvastatin is an HMG-CoA reductase inhibitor, also known as a “statin.” It works by reducing the production of certain fatty substances in the body, including cholesterol.

TELMISARTAN

TELMISARTAN cas no 144701-48-4
Treating high blood pressure alone or with other medicines. It is also used to reduce the risk of heart attack, stroke, or death due to heart problems in certain patients. It may also be used for other conditions as determined by your doctor.Telmisartan is an angiotensin II receptor blocker (ARB). It works by relaxing blood vessels, which helps to lower blood pressure.

TERBUTALINE SULPHATE

TERBUTALINE SULPHATE cas no 23031-25-6
Treating or preventing symptoms caused by spasms or contractions of the muscles around the bronchioles (air tubes) associated with asthma, bronchitis, and emphysema. It may also be used for other conditions as determined by your doctor.Terbutaline is a bronchodilator. It works by dilating (opening) the bronchioles of the lungs by relaxing the muscles around them. This allows for easier airflow into and out of the lungs.

TIMOLOL MALEATE

TIMOLOL MALEATE cas no 26839-75-8
Treating high blood pressure. It is also used to help prevent a second heart attack in patients who have survived a first heart attack and are stable and to prevent migraines. It may also be used for other conditions as determined by your doctor.Timolol is a beta-blocker. It works by interfering with body chemicals that shrink blood vessels and interfere with normal heart contractions.

TOLPERISONE

TOLPERISONE cas no 728-88-1
Tolperisone, a piperidine derivative, is a centrally acting muscle relaxant.

TRAMADOL HCL

TRAMADOL HCL cas no 27203-92-5
Tramadol is a narcotic-like pain reliever. Tramadol is used to treat moderate to severe pain.The extended-release form of tramadol is for around-the-clock treatment of pain. This form of tramadol is not for use on an as-needed basis for pain.

VOGLIBOSE

VOGLIBOSE cas no 83480-29-9
Voglibose is an alpha-glucosidase inhibitor used for lowering post-prandial blood glucose levels in people with diabetes mellitus. Voglibose delays the absorption of glucose thereby reducing the risk of macrovascular complications.